Mechanical stress induces elastic fibre disruption and cartilage matrix increase in ligamentum flavum

Lumbar spinal stenosis (LSS) is one of the most frequent causes of low back pain and gait disturbance in the elderly. Ligamentum flavum (LF) hypertrophy is the main pathomechanism of LSS, but the reason for its occurrence is not clearly elucidated. In this study, we established a novel animal model...

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Publicado en:Sci Rep
Main Authors: Hayashi, Kazunori, Suzuki, Akinobu, Abdullah Ahmadi, Sayed, Terai, Hidetomi, Yamada, Kentaro, Hoshino, Masatoshi, Toyoda, Hiromitsu, Takahashi, Shinji, Tamai, Koji, Ohyama, Shoichiro, Javid, Akgar, Suhrab Rahmani, Mohammad, Hasib, Maruf Mohammad, Nakamura, Hiroaki
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638934/
https://ncbi.nlm.nih.gov/pubmed/29026131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13360-w
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