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MCT1 and MCT4 Expression and Lactate Flux Activity Increase During White and Brown Adipogenesis and Impact Adipocyte Metabolism

Adipose tissue takes up glucose and releases lactate, thereby contributing significantly to systemic glucose and lactate homeostasis. This implies the necessity of upregulation of net acid and lactate flux capacity during adipocyte differentiation and function. However, the regulation of lactate- an...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Petersen, Charlotte, Nielsen, Mette D., Andersen, Elise S., Basse, Astrid L., Isidor, Marie S., Markussen, Lasse K., Viuff, Birgitte M., Lambert, Ian H., Hansen, Jacob B., Pedersen, Stine F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638914/
https://ncbi.nlm.nih.gov/pubmed/29026134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13298-z
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