ID3 regulates the MDC1-mediated DNA damage response in order to maintain genome stability

MDC1 plays a critical role in the DNA damage response (DDR) by interacting directly with several factors including γ-H2AX. However, the mechanism by which MDC1 is recruited to damaged sites remains elusive. Here, we show that MDC1 interacts with a helix–loop–helix (HLH)-containing protein called inh...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Lee, Jung-Hee, Park, Seon-Joo, Hariharasudhan, Gurusamy, Kim, Min-Ji, Jung, Sung Mi, Jeong, Seo-Yeon, Chang, In-Youb, Kim, Cheolhee, Kim, Eunae, Yu, Jihyeon, Bae, Sangsu, You, Ho Jin
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638908/
https://ncbi.nlm.nih.gov/pubmed/29026069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01051-z
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