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Mitophagy in maintaining skeletal muscle mitochondrial proteostasis and metabolic health with ageing

Skeletal muscle is important for overall functionality and health. Ageing is associated with an accumulation of damage to mitochondrial DNA and proteins. In particular, damage to mitochondrial proteins in skeletal muscle, which is a loss of mitochondrial proteostasis, contributes to tissue dysfuncti...

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Bibliografske podrobnosti
izdano v:J Physiol
Main Authors: Drake, Joshua C., Yan, Zhen
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638883/
https://ncbi.nlm.nih.gov/pubmed/28795394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP274337
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