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Opiate use inhibits TLR9 signaling pathway in vivo: possible role in pathogenesis of HIV-1 infection
The molecular mechanism of opiate use promoting HIV-1 infection is not fully understood. TLR9 is expressed in many immune cells, including monocytes, macrophages, which can recognize viruses and viral products and consequently induce the production of antiviral factors and initiate immune responses....
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5638828/ https://ncbi.nlm.nih.gov/pubmed/29026137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12066-3 |
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