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Improving membrane protein expression and function using genomic edits

Expression of membrane proteins often leads to growth inhibition and perturbs central metabolism and this burden varies with the protein being overexpressed. There are also known strain backgrounds that allow greater expression of membrane proteins but that differ in efficacy across proteins. We hyp...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Jensen, Heather M., Eng, Thomas, Chubukov, Victor, Herbert, Robin A., Mukhopadhyay, Aindrila
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638813/
https://ncbi.nlm.nih.gov/pubmed/29026162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12901-7
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