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Dopamine negatively modulates the NCA ion channels in C. elegans

The NALCN/NCA ion channel is a cation channel related to voltage-gated sodium and calcium channels. NALCN has been reported to be a sodium leak channel with a conserved role in establishing neuronal resting membrane potential, but its precise cellular role and regulation are unclear. The Caenorhabdi...

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Bibliografske podrobnosti
izdano v:PLoS Genet
Main Authors: Topalidou, Irini, Cooper, Kirsten, Pereira, Laura, Ailion, Michael
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638609/
https://ncbi.nlm.nih.gov/pubmed/28968387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007032
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