HIV-specific CD8 T cells express low levels of IL-7Rα: Implications for HIV-specific T cell memory

Chronic infections in mice can result in defects in memory CD8 T cell properties including low expression of the IL-7Rα (CD127). To determine whether defects in memory CD8 T cell formation exist during human chronic infections and to what extent these defects may be allele-or epitope-specific, we co...

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Publicado no:Virology
Main Authors: Wherry, E. John, Day, Cheryl L., Draenert, Rika, Miller, Joseph D., Kiepiela, Photini, Woodberry, Tonia, Brander, Christian, Addo, Marylyn, Klenerman, Paul, Ahmed, Rafi, Walker, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638446/
https://ncbi.nlm.nih.gov/pubmed/16860834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.06.017
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