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Regeneration of glycocalyx by heparan sulfate and sphingosine 1-phosphate restores inter-endothelial communication

Vasculoprotective endothelium glycocalyx (GCX) shedding plays a critical role in vascular disease. Previous work demonstrated that GCX degradation disrupts endothelial cell (EC) gap junction connexin (Cx) proteins, likely blocking interendothelial molecular transport that maintains EC and vascular t...

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Pubblicato in:PLoS One
Autori principali: Mensah, Solomon A., Cheng, Ming J., Homayoni, Homa, Plouffe, Brian D., Coury, Arthur J., Ebong, Eno E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638341/
https://ncbi.nlm.nih.gov/pubmed/29023478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186116
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