Crystal structure of an HIV-binding recombinant fragment of human CD4

CD4 glycoprotein on the surface of T cells helps in the immune response and is the receptor for HIV infection. The structure of a soluble fragment of CD4 determined at 2.3 Å resolution reveals that the molecule has two intimately associated immunoglobulin-like domains. Residues implicated in HIV rec...

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Udgivet i:Nature
Main Authors: Ryu, Seong-Eon, Kwong, Peter D., Truneh, Alemseged, Porter, Terence G., Arthos, James, Rosenberg, Martin, Dai, Xiaoping, Xuong, Nguyen-huu, Axel, Richard, Sweet, Raymond W., Hendrickson, Wayne A.
Format: Artigo
Sprog:Inglês
Udgivet: 1990
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638305/
https://ncbi.nlm.nih.gov/pubmed/2247146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/348419a0
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