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Eluxadoline in irritable bowel syndrome with diarrhea: rationale, evidence and place in therapy

Irritable bowel syndrome (IBS) is the most common gastrointestinal (GI) disorder worldwide, however treatment options for diarrhea-predominant IBS (IBS-D) remain limited. Eluxadoline, a µ- and κ-opioid receptor agonist and δ-opioid receptor antagonist, was recently approved for the treatment of IBS-...

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Detalles Bibliográficos
Publicado en:Ther Adv Chronic Dis
Main Authors: Barshop, Kenneth, Staller, Kyle
Formato: Artigo
Idioma:Inglês
Publicado: SAGE Publications 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638229/
https://ncbi.nlm.nih.gov/pubmed/29090081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040622317714389
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