Identifying direct contacts between protein complex subunits from their conditional dependence in proteomics datasets

Determining the three dimensional arrangement of proteins in a complex is highly beneficial for uncovering mechanistic function and interpreting genetic variation in coding genes comprising protein complexes. There are several methods for determining co-complex interactions between proteins, among t...

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Pubblicato in:PLoS Comput Biol
Autori principali: Drew, Kevin, Müller, Christian L., Bonneau, Richard, Marcotte, Edward M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638211/
https://ncbi.nlm.nih.gov/pubmed/29023445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005625
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