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Assessing and predicting drug-induced anticholinergic risks: an integrated computational approach
BACKGROUND: Anticholinergic (AC) adverse drug events (ADEs) are caused by inhibition of muscarinic receptors as a result of designated or off-target drug–receptor interactions. In practice, AC toxicity is assessed primarily based on clinician experience. The goal of this study was to evaluate a nove...
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Publicado no: | Ther Adv Drug Saf |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
SAGE Publications
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5638173/ https://ncbi.nlm.nih.gov/pubmed/29090085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2042098617725267 |
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