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MiSynPat: An integrated knowledge base linking clinical, genetic, and structural data for disease‐causing mutations in human mitochondrial aminoacyl‐tRNA synthetases

Numerous mutations in each of the mitochondrial aminoacyl‐tRNA synthetases (aaRSs) have been implicated in human diseases. The mutations are autosomal and recessive and lead mainly to neurological disorders, although with pleiotropic effects. The processes and interactions that drive the etiology of...

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Detalhes bibliográficos
Publicado no:Hum Mutat
Main Authors: Moulinier, Luc, Ripp, Raymond, Castillo, Gaston, Poch, Olivier, Sissler, Marie
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638098/
https://ncbi.nlm.nih.gov/pubmed/28608363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23277
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