DNA Cross-Bridging Shapes a Single Nucleus from a Set of Mitotic Chromosomes

Eukaryotic cells store their chromosomes in a single nucleus. This is important to maintain genomic integrity, as chromosomes packaged into separate nuclei (micronuclei) are prone to massive DNA damage. During mitosis, higher eukaryotes disassemble their nucleus and release individualized chromosome...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Samwer, Matthias, Schneider, Maximilian W.G., Hoefler, Rudolf, Schmalhorst, Philipp S., Jude, Julian G., Zuber, Johannes, Gerlich, Daniel W.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638020/
https://ncbi.nlm.nih.gov/pubmed/28841419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.07.038
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