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Lack of Efficacy of Liposomal Amphotericin B Against Acute and Chronic Trypanosoma cruzi Infection in Mice

Acute and chronic infection with Trypanosoma cruzi affects millions of people. The current therapeutic options are highly toxic and often not effective. Liposomal amphotericin B (LAMB) has been demonstrated previously to have some activity in murine models. In our studies, higher dosages given multi...

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Détails bibliographiques
Publié dans:Am J Trop Med Hyg
Auteurs principaux: Clemons, Karl V., Sobel, Raymond A., Martinez, Marife, Correa-Oliveira, Rodrigo, Stevens, David A.
Format: Artigo
Langue:Inglês
Publié: The American Society of Tropical Medicine and Hygiene 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637596/
https://ncbi.nlm.nih.gov/pubmed/28820684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.16-0975
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