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Synchronous long-term oscillations in a synthetic gene circuit

Synthetically engineered genetic circuits can perform a wide range of tasks but generally with lower accuracy than natural systems. Here we revisited the first synthetic genetic oscillator, the repressilator(1), and modified it based on principles from stochastic chemistry in single cells. Specifica...

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Vydáno v:Nature
Hlavní autoři: Potvin-Trottier, Laurent, Lord, Nathan D., Vinnicombe, Glenn, Paulsson, Johan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637407/
https://ncbi.nlm.nih.gov/pubmed/27732583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature19841
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