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Plasmin reduces fibronectin deposition by mesangial cells in a protease-activated receptor-1 independent manner
BACKGROUND: Protease-activated receptor-1 (PAR-1) potentiates diabetic nephropathy (DN) as evident from reduced kidney injury in diabetic PAR-1 deficient mice. Although thrombin is the prototypical PAR-1 agonist, anticoagulant treatment does not limit DN in experimental animal models suggesting that...
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| Publicado no: | Biochem Biophys Rep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5637235/ https://ncbi.nlm.nih.gov/pubmed/29114573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2017.03.009 |
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