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In Vivo Metabolic Trapping Radiotracers for Imaging Monoamine Oxidase-A and –B Enzymatic Activity

The isozymes of monoamine oxidase (MAO-A and MAO-B) are important enzymes involved in the metabolism of numerous biogenic amines, including the neurotransmitters serotonin, dopamine and norepinephrine. Recently, changes in concentrations of MAO-B have been proposed as an in vivo marker of neuroinfla...

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Bibliographic Details
Published in:ACS Chem Neurosci
Main Authors: Brooks, Allen F., Shao, Xia, Quesada, Carole A., Sherman, Phillip, Scott, Peter J.H., Kilbourn, Michael R.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637101/
https://ncbi.nlm.nih.gov/pubmed/26393369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.5b00223
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