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Acceleration of pancreatic tumorigenesis under immunosuppressive microenvironment induced by Reg3g overexpression

Reg3g is a potential risk for pancreatic ductal adenocarcinoma (PDAC). We previously demonstrated that Reg3g promoted pancreatic carcinogenesis via a STAT3 signaling pathway in a murine model of chronic pancreatitis. Whether the immune response is involved in tumorigenesis induced by Reg3g remains u...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Liu, Xiulan, Zhou, Zhongshi, Cheng, Qi, Wang, Hongjie, Cao, Hui, Xu, Qianqian, Tuo, Yali, Jiang, Li, Zou, You, Ren, Hongyu, Xiang, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636971/
https://ncbi.nlm.nih.gov/pubmed/28880262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.424
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