MKK6 controls T3-mediated browning of white adipose tissue

Increasing the thermogenic capacity of adipose tissue to enhance organismal energy expenditure is considered a promising therapeutic strategy to combat obesity. Here, we report that expression of the p38 MAPK activator MKK6 is elevated in white adipose tissue of obese individuals. Using knockout ani...

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Publicado no:Nat Commun
Main Authors: Matesanz, Nuria, Bernardo, Edgar, Acín-Pérez, Rebeca, Manieri, Elisa, Pérez-Sieira, Sonia, Hernández-Cosido, Lourdes, Montalvo-Romeral, Valle, Mora, Alfonso, Rodríguez, Elena, Leiva-Vega, Luis, Lechuga-Vieco, Ana Victoria, Ruiz-Cabello, Jesús, Torres, Jorge L., Crespo-Ruiz, Maria, Centeno, Francisco, Álvarez, Clara V., Marcos, Miguel, Enríquez, Jose Antonio, Nogueiras, Ruben, Sabio, Guadalupe
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636784/
https://ncbi.nlm.nih.gov/pubmed/29021624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00948-z
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