The glucocorticoid receptor in monocyte-derived macrophages is critical for cardiac infarct repair and remodeling

Cell- and tissue-specific actions of glucocorticoids are mediated by the glucocorticoid receptor. Here, we demonstrate that the glucocorticoid receptor (GR) in macrophages is essential for cardiac healing after myocardial infarction. Compared with GR(flox) (wild-type controls), GR(LysMCre) mice that...

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Detaylı Bibliyografya
Yayımlandı:FASEB J
Asıl Yazarlar: Galuppo, Paolo, Vettorazzi, Sabine, Hövelmann, Julian, Scholz, Claus-Jürgen, Tuckermann, Jan Peter, Bauersachs, Johann, Fraccarollo, Daniela
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Federation of American Societies for Experimental Biology 2017
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636710/
https://ncbi.nlm.nih.gov/pubmed/28768721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700317R
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