The glucocorticoid receptor in monocyte-derived macrophages is critical for cardiac infarct repair and remodeling

Cell- and tissue-specific actions of glucocorticoids are mediated by the glucocorticoid receptor. Here, we demonstrate that the glucocorticoid receptor (GR) in macrophages is essential for cardiac healing after myocardial infarction. Compared with GR(flox) (wild-type controls), GR(LysMCre) mice that...

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Detalles Bibliográficos
Publicado en:FASEB J
Main Authors: Galuppo, Paolo, Vettorazzi, Sabine, Hövelmann, Julian, Scholz, Claus-Jürgen, Tuckermann, Jan Peter, Bauersachs, Johann, Fraccarollo, Daniela
Formato: Artigo
Idioma:Inglês
Publicado: Federation of American Societies for Experimental Biology 2017
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636710/
https://ncbi.nlm.nih.gov/pubmed/28768721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700317R
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