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An acceptor analogue of β-1,4-galactosyltransferase: Substrate, inhibitor, or both?

Many glycosyltransferase inhibitors in the literature are structurally derived from the donor or acceptor substrate of the respective enzyme. A representative example is 2-naphthyl β-d-GlcNAc, a synthetic GlcNAc glycoside that has been reported as a galactosyltransferase inhibitor. This GlcNAc deriv...

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Bibliografiska uppgifter
I publikationen:Carbohydr Res
Huvudupphovsmän: Jiang, Jingqian, Wagner, Gerd K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636615/
https://ncbi.nlm.nih.gov/pubmed/28910600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2017.08.012
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