Estimation of kinship coefficient in structured and admixed populations using sparse sequencing data

Knowledge of biological relatedness between samples is important for many genetic studies. In large-scale human genetic association studies, the estimated kinship is used to remove cryptic relatedness, control for family structure, and estimate trait heritability. However, estimation of kinship is c...

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Publicat a:PLoS Genet
Autors principals: Dou, Jinzhuang, Sun, Baoluo, Sim, Xueling, Hughes, Jason D., Reilly, Dermot F., Tai, E. Shyong, Liu, Jianjun, Wang, Chaolong
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636172/
https://ncbi.nlm.nih.gov/pubmed/28961250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007021
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