Defective decidualization during and after severe preeclampsia reveals a possible maternal contribution to the etiology

In preeclampsia (PE), cytotrophoblast (CTB) invasion of the uterus and spiral arteries is often shallow. Thus, the placenta’s role has been a focus. In this study, we tested the hypothesis that decidual defects are an important determinant of the placental phenotype. We isolated human endometrial st...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Garrido-Gomez, Tamara, Dominguez, Francisco, Quiñonero, Alicia, Diaz-Gimeno, Patricia, Kapidzic, Mirhan, Gormley, Matthew, Ona, Katherine, Padilla-Iserte, Pablo, McMaster, Michael, Genbacev, Olga, Perales, Alfredo, Fisher, Susan J., Simón, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5635883/
https://ncbi.nlm.nih.gov/pubmed/28923940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706546114
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