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Limitations of Current in Vivo Mouse Models for the Study of Chikungunya Virus Pathogenesis

Chikungunya virus (CHIKV) is an arthropod-borne alphavirus that causes febrile chikungunya fever (CHIKF) in humans. This disease is debilitating and characterized by acute fever onset and chronic incapacitating polyarthralgia. CHIKF pathogenesis remains poorly defined with no approved vaccines and t...

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發表在:Med Sci (Basel)
Main Authors: Chan, Yi-Hao, Lum, Fok-Moon, Ng, Lisa F. P.
格式: Artigo
語言:Inglês
出版: MDPI 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5635755/
https://ncbi.nlm.nih.gov/pubmed/29083392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/medsci3030064
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