Regulation of PLK1 through competition between hnRNPK, miR-149-3p and miR-193b-5p

Polo-like kinase 1 (PLK1) is a critical regulator of cell cycle progression and apoptosis. However, its regulation remains poorly understood. In the present study, we investigated the molecular mechanism underlying the post-transcriptional regulation of PLK1. We observed that heterogeneous nuclear r...

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Publicat a:Cell Death Differ
Autors principals: Shin, Chang Hoon, Lee, Hong, Kim, Hye Ree, Choi, Kyung Hee, Joung, Je-Gun, Kim, Hyeon Ho
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5635212/
https://ncbi.nlm.nih.gov/pubmed/28708135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.106
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