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Sodium fluorocitrate having protective effect on palmitate-induced beta cell death improves hyperglycemia in diabetic db/db mice

Beta cell loss and insulin resistance play roles in the pathogenesis of type 2 diabetes. Elevated levels of free fatty acids in plasma might contribute to the loss of beta cells. The objective of this study was to find a chemical that could protect against palmitate-induced beta cell death and inves...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jung, Ik-Rak, Choi, Sung-E., Hong, Seung A., Hwang, Yoonjung, Kang, Yup
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5635019/
https://ncbi.nlm.nih.gov/pubmed/29018279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13365-5
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