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Contextual tumor suppressor function of T cell death-associated gene 8 (TDAG8) in hematological malignancies

BACKGROUND: Extracellular acidosis is a condition found within the tumor microenvironment due to inadequate blood perfusion, hypoxia, and altered tumor cell metabolism. Acidosis has pleiotropic effects on malignant progression; therefore it is essential to understand how acidosis exerts its diverse...

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Vydáno v:J Transl Med
Hlavní autoři: Justus, Calvin R., Sanderlin, Edward J., Dong, Lixue, Sun, Tianai, Chi, Jen-Tsan, Lertpiriyapong, Kvin, Yang, Li V.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5634876/
https://ncbi.nlm.nih.gov/pubmed/29017562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1305-6
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