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Localized Adult Ewing Sarcoma: Favorable Outcomes with Alternating Vincristine, Doxorubicin, Cyclophosphamide, and Ifosfamide, Etoposide (VDC/IE)‐Based Multimodality Therapy

BACKGROUND. In children with localized Ewing sarcoma (ES), addition of ifosfamide and etoposide to cyclophosphamide, doxorubicin, and vincristine (VDC/IE) improved 5‐year overall survival (OS) to 70%–80%. Prior to delivery of VDC/IE in adults, 5‐year OS was <50%. We reviewed our institutional out...

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Veröffentlicht in:Oncologist
Hauptverfasser: Pretz, Jennifer L., Barysauskas, Constance M., George, Suzanne, Hornick, Jason L., Raut, Chandrajit. P., Chen, Yen-Lin E., Marcus, Karen J., Choy, Edwin, Hornicek, Francis, Ready, John E., DeLaney, Thomas F., Baldini, Elizabeth H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: AlphaMed Press 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5634761/
https://ncbi.nlm.nih.gov/pubmed/28550026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2016-0463
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