Reversibility of the effects of natalizumab on peripheral immune cell dynamics in MS patients

OBJECTIVE: To characterize the reversibility of natalizumab-mediated changes in pharmacokinetics/pharmacodynamics in patients with multiple sclerosis (MS) following therapy interruption. METHODS: Pharmacokinetic/pharmacodynamic data were collected in the Safety and Efficacy of Natalizumab in the Tre...

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Veröffentlicht in:Neurology
Hauptverfasser: Plavina, Tatiana, Muralidharan, Kumar Kandadi, Kuesters, Geoffrey, Mikol, Daniel, Evans, Karleyton, Subramanyam, Meena, Nestorov, Ivan, Chen, Yi, Dong, Qunming, Ho, Pei-Ran, Amarante, Diogo, Adams, Alison, De Sèze, Jerome, Fox, Robert, Gold, Ralf, Jeffery, Douglas, Kappos, Ludwig, Montalban, Xavier, Weinstock-Guttman, Bianca, Hartung, Hans-Peter, Cree, Bruce A.C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5634662/
https://ncbi.nlm.nih.gov/pubmed/28916537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000004485
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