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Perimenopause and emergence of an Alzheimer’s bioenergetic phenotype in brain and periphery

After advanced age, female sex is the major risk factor for Alzheimer’s disease (AD). The biological mechanisms underlying the increased AD risk in women remain largely undetermined. Preclinical studies identified the perimenopause to menopause transition, a neuroendocrine transition state unique to...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mosconi, Lisa, Berti, Valentina, Guyara-Quinn, Crystal, McHugh, Pauline, Petrongolo, Gabriella, Osorio, Ricardo S., Connaughty, Christopher, Pupi, Alberto, Vallabhajosula, Shankar, Isaacson, Richard S., de Leon, Mony J., Swerdlow, Russell H., Brinton, Roberta Diaz
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5634623/
https://ncbi.nlm.nih.gov/pubmed/29016679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185926
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