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Stem Cell Plasticity and Niche Dynamics in Cancer Progression

OBJECTIVE: Cancer stem cells (CSCs) have been hypothesized to initiate and drive tumor growth and recurrence due to their self-renewal ability. If correct, this hypothesis implies that successful therapy must focus primarily on eradication of this CSC fraction. However, recent evidence suggests stem...

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Detalhes bibliográficos
Publicado no:IEEE Trans Biomed Eng
Main Authors: Picco, Noemi, Gatenby, Robert A., Anderson, Alexander R. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5634531/
https://ncbi.nlm.nih.gov/pubmed/28113244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/TBME.2016.2607183
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