An extremely rare case of concurrent BRAF V600E mutation driven hairy cell leukemia and melanoma: case report and review of literature

BRAF protein is a serine/threonine kinase with 766 amino acids. Approximately 15% of human cancers harbor BRAF mutations as well as other BRAF anomalies (amplifications, fusions). Somatic mutations mainly occur in the catalytic kinase domain (CR3), and the predominant mutation is p.V600E which is th...

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Detalles Bibliográficos
Publicado en:Autops Case Rep
Main Authors: Ghorbani-Aghbolaghi, Amir, Lechpammer, Mirna, Ali, Saba F., Ku, Nam K., Dwyre, Denis M., Rashidi, Hooman H.
Formato: Artigo
Idioma:Inglês
Publicado: São Paulo, SP: Universidade de São Paulo, Hospital Universitário 2017
Assuntos:
Article / Clinical Case Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5634429/
https://ncbi.nlm.nih.gov/pubmed/29043205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4322/acr.2017.032
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