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Large-scale crystallization and neutron crystallographic analysis of HSP70 in complex with ADP
HSP70 belongs to the heat-shock protein family and binds to unfolded proteins, driven by ATP hydrolysis, in order to prevent aggregation. Previous X-ray crystallographic analyses of HSP70 have shown that HSP70 binds to ADP with internal water molecules. In order to elucidate the role of the water mo...
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| Publicado no: | Acta Crystallogr F Struct Biol Commun |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5633922/ https://ncbi.nlm.nih.gov/pubmed/28994403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X1701264X |
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