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PARP-1 and p53 Regulate the Increased Susceptibility to Oxidative Death of Lymphocytes from MCI and AD Patients

Mild cognitive impairment (MCI) is a clinically detectable initial stage of cognitive deterioration with a high conversion rate to dementia. There is increasing evidence that some of the cerebral alterations present in Alzheimer type dementia can be found in peripheral tissues. We have previously sh...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Salech, Felipe, Ponce, Daniela P., SanMartín, Carol D., Rogers, Nicole K., Chacón, Carlos, Henríquez, Mauricio, Behrens, Maria I.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5633596/
https://ncbi.nlm.nih.gov/pubmed/29051731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2017.00310
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