NF-κB c-Rel Is Crucial for the Regulatory T Cell Immune Checkpoint in Cancer

Regulatory T cells (Tregs) play a pivotal role in the inhibition of anti-tumor immune responses. Understanding the mechanisms governing Treg homeostasis may therefore be important for development of effective tumor immunotherapy. We have recently demonstrated a key role for the canonical nuclear fac...

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Vydáno v:Cell
Hlavní autoři: Grinberg-Bleyer, Yenkel, Oh, Hyunju, Desrichard, Alexis, Bhatt, Dev M., Caron, Rachel, Chan, Timothy A., Schmid, Roland M., Hayden, Matthew S., Klein, Ulf, Ghosh, Sankar
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5633372/
https://ncbi.nlm.nih.gov/pubmed/28886380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.08.004
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