Susceptibility to Mycobacterium ulcerans Disease (Buruli ulcer) Is Associated with IFNG and iNOS Gene Polymorphisms

Buruli ulcer (BU) is a chronic necrotizing disease of the skin and subcutaneous fat tissue. The causative agent, Mycobacterium ulcerans, produces mycolactone, a macrolide toxin, which causes apoptosis of mammalian cells. Only a small proportion of individuals exposed to M. ulcerans develop clinical...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Bibert, Stéphanie, Bratschi, Martin W., Aboagye, Samuel Y., Collinet, Emilie, Scherr, Nicole, Yeboah-Manu, Dorothy, Beuret, Christian, Pluschke, Gerd, Bochud, Pierre-Yves
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5632961/
https://ncbi.nlm.nih.gov/pubmed/29046669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.01903
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