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Cytotoxic (salen)ruthenium(iii) anticancer complexes exhibit different modes of cell death directed by axial ligands

Two novel series of (salen)ruthenium(iii) complexes bearing guanidine and amidine axial ligands were synthesized, characterized, and evaluated for anticancer activity. In vitro cytotoxicity tests demonstrate that these complexes are cytotoxic against various cancer cell lines and the leading complex...

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Publicat a:Chem Sci
Autors principals: Li, Cai, Ip, Kwok-Wa, Man, Wai-Lun, Song, Dan, He, Ming-Liang, Yiu, Shek-Man, Lau, Tai-Chu, Zhu, Guangyu
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5632802/
https://ncbi.nlm.nih.gov/pubmed/29147511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc02205k
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