Mechanisms of action and in vivo antibacterial efficacy assessment of five novel hybrid peptides derived from Indolicidin and Ranalexin against Streptococcus pneumoniae

BACKGROUND: Antimicrobial peptides (AMPs) are of great potential as novel antibiotics for the treatment of broad spectrum of pathogenic microorganisms including resistant bacteria. In this study, the mechanisms of action and the therapeutic efficacy of the hybrid peptides were examined. METHODS: TEM...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PeerJ
Päätekijät: Jindal, Hassan Mahmood, Zandi, Keivan, Ong, Kien Chai, Velayuthan, Rukumani Devi, Rasid, Sara Maisha, Samudi Raju, Chandramathi, Sekaran, Shamala Devi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: PeerJ Inc. 2017
Aiheet:
Microbiology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5632533/
https://ncbi.nlm.nih.gov/pubmed/29018620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.3887
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