Regulation of a Coupled MARCKS–PI3K Lipid Kinase Circuit by Calmodulin: Single-Molecule Analysis of a Membrane-Bound Signaling Module

Amoeboid cells that employ chemotaxis to travel up an attractant gradient possess a signaling network assembled on the leading edge of the plasma membrane that senses the gradient and remodels the actin mesh and cell membrane to drive movement in the appropriate direction. In leukocytes such as macr...

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Veröffentlicht in:Biochemistry
Hauptverfasser: Ziemba, Brian P., Swisher, G. Hayden, Masson, Glenn, Burke, John E., Williams, Roger L., Falke, Joseph J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5632315/
https://ncbi.nlm.nih.gov/pubmed/27933776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00908
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