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Passive Immunization with Anti-Pertussis Toxin Humanized Monoclonal Antibody Mitigates Clinical Signs of Pertussis Infection in Newborn Baboons

BACKGROUND: Pertussis is a significant mortality risk in the developing world, killing up to 200,000 infants annually. Maternal vaccination as a strategy to protect newborns has shown some success, but is unlikely to capture all eligible mothers. Hu1B7 is a monoclonal antibody (mAb) that potently ne...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Maynard, Jennifer, Nguyen, Annalee, Wolf, Roman, Papin, James, Connelly, Sheila, Kaleko, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5631686/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofx162.009
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