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Aberrant Autophagy in Macrophages and Astrocytes after HIV Nef or Antiretroviral Treatment: Contribution to the Pathogenesis of HIV-associated Neurocognitive Disorders

BACKGROUND: Despite antiretroviral therapy (ART), HIV-associated neurocognitive disorders (HAND) still affect 40–70% of HIV-infected people. The pathogenesis of HAND is multi-factorial and poorly understood. Macroautophagy is a cellular self-digestion process with essential roles in defense against...

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Publicat a:Open Forum Infect Dis
Autors principals: Cheney, Laura, Calderon, Tina, Cuervo, Ana Maria, Berman, Joan W
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5631599/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofx163.407
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