A Whole Genome Sequencing (WGS) Approach to Predict Daptomycin (DAP) Susceptibility of Enterococcus faecium

BACKGROUND: We have previously shown that vancomycin-resistant E. faecium (VRE) with DAP MICs close to the breakpoint (4 µg/mL) harbor genetic changes associated with DAP resistance (DAP-R). Further, DAP MIC was a predictor of poor microbiological eradication in patients with VRE bacteremia treated...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Contreras, German, Diaz, Lorena, Rios, Rafael, Reyes, Katherine C, Kamboj, Mini, Lewis, Jessica, Rincon, Sandra, Reyes, Jinnethe, Carvajal, Lina Paola, Panesso, Diana, Sifri, Costi D, Zervos, Marcus, Pamer, Eric, Tran, Truc T, Shelburne, Samuel, Munita, Jose, Arias, Cesar
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5631548/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofx163.1580
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