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Bezlotoxumab (BEZ) for Prevention of Clostridium difficile Infection (CDI) Recurrence (rCDI): Distinguishing Relapse from Reinfection with Whole Genome Sequencing (WGS)

BACKGROUND: Bezlotoxumab (BEZ) and actoxumab (ACT) are monoclonal antibodies against C. difficile toxins B and A, respectively. Patients receiving a single infusion of BEZ alone or with ACT in the MODIFY I/II trials showed an absolute 10% (relative ~40%) reduction in rCDI over 12-weeks compared with...

詳細記述

保存先:
書誌詳細
出版年:Open Forum Infect Dis
主要な著者: Dorr, Mary Beth, Zeng, Zhen, Wilcox, Mark, Li, Junhua, Poxton, Ian, Zhao, Hailong, Li, Xiaoyun, Guris, Dalya, Shaw, Peter
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5631366/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofx163.967
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