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In Vivo Efficacy of Humanized Exposures of Cefiderocol Compared with Cefepime (FEP) and Meropenem (MEM) against Gram-negative Bacteria in a Murine Thigh Model
BACKGROUND: Cefiderocol (S-649266) is a novel siderophore cephalosporin under development by Shionogi (Osaka, Japan). Previous studies have demonstrated cefiderocol efficacy against a diverse population of Gram-negative bacteria with MICs ≤ 4 μg/mL. Our aim was to further define the agent’s clinical...
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| Pubblicato in: | Open Forum Infect Dis |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5631164/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofx163.1216 |
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