Activity of Plazomicin against Enterobacteriaceae Isolates Collected in the United States Including Isolates Carrying Aminoglycoside-Modifying Enzymes Detected by Whole Genome Sequencing

BACKGROUND: Plazomicin (PLZ) is a next-generation aminoglycoside (AMG) stable against aminoglycoside-modifying enzymes (AME) that completed Phase 3 studies for complicated urinary tract infections and serious infections due to carbapenem-resistant Enterobacteriaceae (ENT). We evaluated the activity...

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Publicat a:Open Forum Infect Dis
Autors principals: Castanheira, Mariana, Deshpande, Lalitagauri M, Hubler, Cory M, Mendes, Rodrigo E, Serio, Alisa W, Krause, Kevin M, Flamm, Robert K
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630809/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofx163.931
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