Enhancing excitatory activity of somatosensory cortex alleviates neuropathic pain through regulating homeostatic plasticity

Central sensitization and network hyperexcitability of the nociceptive system is a basic mechanism of neuropathic pain. We hypothesize that development of cortical hyperexcitability underlying neuropathic pain may involve homeostatic plasticity in response to lesion-induced somatosensory deprivation...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Xiong, Wenhui, Ping, Xingjie, Ripsch, Matthew S., Chavez, Grace Santa Cruz, Hannon, Heidi Elise, Jiang, Kewen, Bao, Chunhui, Jadhav, Vaishnavi, Chen, Lifang, Chai, Zhi, Ma, Cungen, Wu, Huangan, Feng, Jianqiao, Blesch, Armin, White, Fletcher A., Jin, Xiaoming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630599/
https://ncbi.nlm.nih.gov/pubmed/28986567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12972-6
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