Impact of sequencing depth and read length on single cell RNA sequencing data of T cells

Single cell RNA sequencing (scRNA-seq) provides great potential in measuring the gene expression profiles of heterogeneous cell populations. In immunology, scRNA-seq allowed the characterisation of transcript sequence diversity of functionally relevant T cell subsets, and the identification of the f...

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Vydáno v:Sci Rep
Hlavní autoři: Rizzetto, Simone, Eltahla, Auda A., Lin, Peijie, Bull, Rowena, Lloyd, Andrew R., Ho, Joshua W. K., Venturi, Vanessa, Luciani, Fabio
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630586/
https://ncbi.nlm.nih.gov/pubmed/28986563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12989-x
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