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Thrombotic Thrombocytopenic Purpura: Pathogenesis, Diagnosis, and Potential Novel Therapeutics

Thrombotic thrombocytopenic purpura (TTP), a potentially fatal clinical syndrome, is primarily caused by autoantibodies against the von Willebrand factor (VWF)-cleaving metalloprotease ADAMTS13. In general, severe deficiency of plasma ADAMTS13 activity (<10 IU/dL) with or without detectable inhib...

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Dades bibliogràfiques
Publicat a:J Thromb Haemost
Autors principals: Saha, Manish, McDaniel, Jenny K., Zheng, X. Long
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630501/
https://ncbi.nlm.nih.gov/pubmed/28662310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13764
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